Through　ligand　modification,　we　have　replaced　the　central　benzene　ring　of　H2TDBA　([1,1＇:　3＇,　1.-terphenyl]-4,4.-dicarboxylicacid)　with　the　pyridine　structurally　related　ligand　H2PDDA　(4,4＇-(pyridine-2,6-diyl)　dibenzoic　acid),　which　makes　the　central　pyridine　ring　of　H2PDDA　more　coplanar　with　two　benzene　rings　on　both　sides　of　the　ligand.　The　modification　results　in　a　dramatically　different　linkage　configuration,　thereby　allowing　structural　changes　to　the　metal-organic　frameworks　(MOFs).　Two　2-D　MOFs,　[Cu(TDBA)(DMA)2].H2O　(BUT-221,　DMA　=　N,N-dimethylacetamide),　and　[Cu　3　(PDDA)　3　(DMA)　2　(H2O)].5H2O　(BUT-223)　have　been　synthesized　through　reactions　of　two　ditopic　carboxylate　ligands　with　Cu(NO3)2.3H2O　under　solvothermal　conditions,　and　characterized　by　single-crystal　X-ray　diffraction,　powder　X-ray　diffraction,　thermogravimetric　analysis　and　infrared　spectroscopy.　Topological　analysis　shows　that　BUT-221　is　a　twofold　parallel　interpenetrating　44　2-D　network　with　a　skl　topology,　while　BUT-223　is　a　2-D　network　with　a　kgm　topology.