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Author:

Jiang, N. (Jiang, N..) | Liu, Q. (Liu, Q..) | Liu, L. (Liu, L..) | Yang, W. W. (Yang, W. W..) | Zeng, Y. (Zeng, Y..)

Indexed by:

SCIE

Abstract:

Background: Pregnant women with chronic hypertension are at increased risk for complications. This study aims to investigate whether calcium channel blockers plus low dosage aspirin therapy can reduce the incidence of complications during pregnancy with chronic hypertension and improve the prognosis of neonates. Materials and Methods: From March 2011 to June 2013,33 patients were selected to join this trial according to the chronic hypertension criteria set by the Preface Bulletin of American College of Obstetricians and Gynecologists, (ACOG). Patients were administrated calcium channel blockers plus low-dosage aspirin and vitamin C. The statistic data of baseline and prognosis from the patients were retrospectively reviewed and compared. Results: Blood pressure of patients was controlled by these medicines with average systolic pressure from 146.3 to 148.7 mmHg and average diastolic pressure from 93.8 to 97.9 mmHg; 39.4% patients complicated mild preeclampsia; however, none of them developed severe preeclampsia or eclampsia, or complicate placental abruption. 30.3% patients delivered at preterm labour; 84.8% patients underwent cesarean section. The neonatal average weight was 3,008 +/- 629.6 g, in which seven neonatal weights were less than 2,500 g. All of the neonatal Apgar scores were 9 to 10 at one to five minutes. Small for gestational age (SGA) occurred in five (15%). Conclusions: Calcium channel blockers can improve the outcome of pregnancy women with chronic hypertension to avoid the occurrence of severe pregnancy complication or neonatal morbidity.

Keyword:

Calcium channel blockers Preeclampsia Chronic hypertension

Author Community:

  • [ 1 ] [Jiang, N.]Jiangsu Univ, Peoples Hosp Kunshan 1, Dept Obstet & Gynecol, Suzhou 215300, Peoples R China
  • [ 2 ] [Liu, Q.]Jiangsu Univ, Peoples Hosp Kunshan 1, Dept Obstet & Gynecol, Suzhou 215300, Peoples R China
  • [ 3 ] [Liu, L.]Jiangsu Univ, Peoples Hosp Kunshan 1, Dept Obstet & Gynecol, Suzhou 215300, Peoples R China
  • [ 4 ] [Yang, W. W.]Soochow Univ, Affiliated Hosp 1, Dept Obstet & Gynecol, Suzhou, Peoples R China
  • [ 5 ] [Zeng, Y.]Beijing Univ Technol, Biomech & Med Informat Inst, Beijing, Peoples R China

Reprint Author's Address:

  • [Liu, L.]Jiangsu Univ, Peoples Hosp Kunshan 1, Dept Obstet & Gynecol, Suzhou 215300, Peoples R China

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Source :

CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY

ISSN: 0390-6663

Year: 2015

Issue: 1

Volume: 42

Page: 79-81

0 . 2 0 0

JCR@2022

ESI Discipline: CLINICAL MEDICINE;

ESI HC Threshold:216

JCR Journal Grade:4

CAS Journal Grade:4

Cited Count:

WoS CC Cited Count: 10

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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