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Author:

Cito, S. (Cito, S..) | Geers, A. J. (Geers, A. J..) | Arroyo, M. P. (Arroyo, M. P..) | Palero, V. R. (Palero, V. R..) | Pallares, J. (Pallares, J..) | Vernet, A. (Vernet, A..) | Blasco, J. (Blasco, J..) | San Roman, L. (San Roman, L..) | Fu, W. (Fu, W..) | Qiao, A. (Qiao, A..) | Janiga, G. (Janiga, G..) | Miura, Y. (Miura, Y..) | Ohta, M. (Ohta, M..) | Mendina, M. (Mendina, M..) | Usera, G. (Usera, G..) | Frangi, A. F. (Frangi, A. F..)

Indexed by:

EI Scopus SCIE

Abstract:

Validation studies are prerequisites for computational fluid dynamics (CFD) simulations to be accepted as part of clinical decision-making. This paper reports on the 2011 edition of the Virtual Intracranial Stenting Challenge. The challenge aimed to assess the reproducibility with which research groups can simulate the velocity field in an intracranial aneurysm, both untreated and treated with five different configurations of high-porosity stents. Particle imaging velocimetry (PIV) measurements were obtained to validate the untreated velocity field. Six participants, totaling three CFD solvers, were provided with surface meshes of the vascular geometry and the deployed stent geometries, and flow rate boundary conditions for all inlets and outlets. As output, they were invited to submit an abstract to the 8th International Interdisciplinary Cerebrovascular Symposium 2011 (ICS'11), outlining their methods and giving their interpretation of the performance of each stent configuration. After the challenge, all CFD solutions were collected and analyzed. To quantitatively analyze the data, we calculated the root-mean-square error (RMSE) over uniformly distributed nodes on a plane slicing the main flow jet along its axis and normalized it with the maximum velocity on the slice of the untreated case (NRMSE). Good agreement was found between CFD and PIV with a NRMSE of 7.28%. Excellent agreement was found between CFD solutions, both untreated and treated. The maximum difference between any two groups (along a line perpendicular to the main flow jet) was 4.0 mm/s, i.e. 4.1% of the maximum velocity of the untreated case, and the average NRMSE was 0.47% (range 0.28-1.03%). In conclusion, given geometry and flow rates, research groups can accurately simulate the velocity field inside an intracranial aneurysm-as assessed by comparison with in vitro measurements-and find excellent agreement on the hemodynamic effect of different stent configurations.

Keyword:

Challenge Stents Intracranial aneurysm Computational fluid dynamics Particle imaging velocimetry

Author Community:

  • [ 1 ] [Cito, S.]Univ Helsinki, Helsinki, Finland
  • [ 2 ] [Cito, S.]Univ Rovira & Virgili, E-43007 Tarragona, Spain
  • [ 3 ] [Pallares, J.]Univ Rovira & Virgili, E-43007 Tarragona, Spain
  • [ 4 ] [Vernet, A.]Univ Rovira & Virgili, E-43007 Tarragona, Spain
  • [ 5 ] [Cito, S.]Univ Pompeu Fabra, Barcelona, Spain
  • [ 6 ] [Geers, A. J.]Univ Pompeu Fabra, Barcelona, Spain
  • [ 7 ] [Frangi, A. F.]Univ Pompeu Fabra, Barcelona, Spain
  • [ 8 ] [Arroyo, M. P.]Univ Zaragoza, Zaragoza, Spain
  • [ 9 ] [Palero, V. R.]Univ Zaragoza, Zaragoza, Spain
  • [ 10 ] [Blasco, J.]Hosp Clin Barcelona, Barcelona, Spain
  • [ 11 ] [San Roman, L.]Hosp Clin Barcelona, Barcelona, Spain
  • [ 12 ] [Fu, W.]Beijing Union Univ, Beijing, Peoples R China
  • [ 13 ] [Qiao, A.]Beijing Univ Technol, Beijing, Peoples R China
  • [ 14 ] [Janiga, G.]Univ Magdeburg, D-39106 Magdeburg, Germany
  • [ 15 ] [Miura, Y.]Tohoku Univ, Tohoku, Japan
  • [ 16 ] [Ohta, M.]Tohoku Univ, Tohoku, Japan
  • [ 17 ] [Mendina, M.]Univ Republica, Montevideo, Uruguay
  • [ 18 ] [Usera, G.]Univ Republica, Montevideo, Uruguay
  • [ 19 ] [Mendina, M.]Univ Sheffield, Sheffield, S Yorkshire, England
  • [ 20 ] [Usera, G.]Univ Sheffield, Sheffield, S Yorkshire, England

Reprint Author's Address:

  • [Cito, S.]Univ Helsinki, Helsinki, Finland

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Source :

ANNALS OF BIOMEDICAL ENGINEERING

ISSN: 0090-6964

Year: 2015

Issue: 1

Volume: 43

Page: 154-167

3 . 8 0 0

JCR@2022

ESI Discipline: MOLECULAR BIOLOGY & GENETICS;

ESI HC Threshold:397

JCR Journal Grade:1

CAS Journal Grade:2

Cited Count:

WoS CC Cited Count: 14

SCOPUS Cited Count: 18

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 7

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