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Author:

Ding, Jinli (Ding, Jinli.) | Liu, Youjun (Liu, Youjun.) (Scholars:刘有军) | Chai, Linjuan (Chai, Linjuan.) | Cao, Xue (Cao, Xue.) | Wang, Feng (Wang, Feng.)

Indexed by:

EI Scopus SCIE

Abstract:

Tetralogy of Fallot is the most common cyanotic congenital heart defect. For severe cases, inserting a systemic to pulmonary shunt, which distributes part of systemic artery blood into the pulmonary artery, is the preferable palliative surgery. Based on the computed tomography images and three-dimensional geometry technologies, two patient-specific anatomical options of systemic to pulmonary shunts including the aorta to pulmonary shunt (APS) and innominate artery to pulmonary shunt (IPS) have been simulated for computational fluid dynamics. The objective of this study was to predict the hemodynamics within the shunts and con firm, through patient-specific simulations, the shunt with the optimal performance. Results indicated that both options created high velocity gradients and pressure gradients at the proximal end of the shunts. Obvious flow recirculation appeared at the inner region near the proximal end of the shunts. Part of the reverse flow from the descending aorta, left subclavian artery, left carotid artery and innominate artery was driven into the shunts during the diastolic period. The IPS provided better balanced and more adequate blood flow distributions between the systemic and pulmonary circulations. The APS provided slightly excessive pulmonary blood flow which can ultimately result in cardiac failure and pulmonary hypertension.

Keyword:

patient-specific Tetralogy of Fallot systemic to pulmonary shunt computational fluid dynamics

Author Community:

  • [ 1 ] [Ding, Jinli]Beijing Univ Technol, Ctr Biomed Engn, Beijing 100124, Peoples R China
  • [ 2 ] [Liu, Youjun]Beijing Univ Technol, Ctr Biomed Engn, Beijing 100124, Peoples R China
  • [ 3 ] [Chai, Linjuan]Beijing Univ Technol, Ctr Biomed Engn, Beijing 100124, Peoples R China
  • [ 4 ] [Cao, Xue]Beijing Univ Technol, Ctr Biomed Engn, Beijing 100124, Peoples R China
  • [ 5 ] [Wang, Feng]Beijing Univ Technol, Ctr Biomed Engn, Beijing 100124, Peoples R China

Reprint Author's Address:

  • 刘有军

    [Liu, Youjun]Beijing Univ Technol, Ctr Biomed Engn, Beijing Pingleyuan 100, Beijing 100124, Peoples R China

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Source :

JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY

ISSN: 0219-5194

Year: 2013

Issue: 1

Volume: 13

0 . 8 0 0

JCR@2022

ESI Discipline: MOLECULAR BIOLOGY & GENETICS;

JCR Journal Grade:4

CAS Journal Grade:4

Cited Count:

WoS CC Cited Count: 3

SCOPUS Cited Count: 6

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 4

Online/Total:1097/10690453
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