The　synthesis　of　modified　bimodal　mesoporous　materials　(BMMs)　with　a　small　pore　size　of　around　2.9　nm　and　a　large　pore　size　of　about　20　nm　has　been　performed　via　post-grafting　methods.　To　study　the　application　of　functionalized　BMMs　in　drug　delivery,　loading　and　releasing　profiles　using　aspirin　as　model　drug　were　carried　out.　XRD,　SEM,　TEM,　N-2　adsorption,　FT-IR,　Si-29-NMR,　TG　and　UV-Vis　spectroscopy　were　used　to　characterize　the　related　samples.　The　post-grafting　modification　was　performed　through　the　weak　chemical　interaction　or　hydrogen　bonding　in　between　OH　groups　of　the　mesopore　surface　and　3-aminopropyltriethoxysilane　(N-TES)　or　3-(2-aminoethylamino)　propyltrimethoxysilane　(NN-TES).　The　results　showed　that　N-TES　groups　with　different　amount　and　NN-TES　groups　were　successfully　incorporated　onto　the　mesopore　surface.　Subsequently,　the　controlled　aspirin　delivery　properties　from　the　resulting　modified　BMMs　were　investigated　in　detail.　The　aspirin　adsorption　experiments　indicated　that　the　adsorption　capacities　of　modified　BMMs　were　improved　with　the　increasing　amount　of　N-TES　groups,　while　the　NN-TES　functionalized　samples　showed　higher　adsorption　capacity　than　N-TES　modified　samples　with　the　same　ratio　of　modification.　The　most　reason　is　that　the　interaction　between　the　NN-TES　groups　and　aspirin　molecules　is　stronger　than　that　between　the　N-TES　groups　and　aspirin　molecules.　The　in　vitro　tests　exhibited　that　aspirin　release　behaviors　mainly　depended　on　the　variation　of　the　amount　and　species　of　the　functional　groups　in　mesoporous　carries.　According　to　the　Korsmeyer-Peppas　model,　it　is　found　that　the　kinetic　release　constant　k　reduced　with　the　increase　amount　of　the　amino　groups　on　the　mesopore　surface　of　modified　BMMs,　suggesting　that　the　aspirin　release　rate　from　the　pores　of　BMMs　was　influenced　directly　by　organic　groups　on　the　surface.　The　release　exponent　n　of　all　the　situations　were　above　0.5,　indicating　the　drug　release　mechanism　followed　a　non-Fickian　model　that　was　diffusion　based.　Therefore,　this　type　of　materials　described　in　this　paper　is　of　strong　potential　for　the　controlled　drug　release　applications.