Protein-protein　interactions　and　recognition　are　the　focal　and　hot　themes　of　the　life　science　field　in　the　21st　century.　Molecular　docking　approach　is　the　effective　computer　modeling　technology　in　the　study　of　this　topic.　Generally,　the　protein-protein　docking　procedure　is　composed　of　four　stages:　searching　of　the　binding　modes　of　the　receptor　and　the　ligand,　filtering　of　docked　modes　to　eliminate　the　irrational　docked　structures,　optimizing　the　structures,　evaluating　the　docked　modes　with　the　refined　scoring　function　and　ranking　them　to　obtain　the　near-native　structures.　Combining　the　research　group＇s　works,　in　terms　of　the　international　and　national　progress　of　protein-protein　docking　approaches,　the　detailed　review　was　made　about　the　four　stages　mentioned　above.　Additionally,　the　existing　major　questions　are　analyzed　and　the　prospects　of　the　future　study　are　made.