The　capability　of　structure　resisting　progressive　collapse　depends　on　controlling　the　dispersion　of　damage　by　uncommon　agency　in　the　part　of　the　structure　and　to　avoid　the　destruction　just　likes　the　Domino　action.　For　the　RC　frame,　when　one　column　under　the　beams　was　broken,　the　key　to　avoid　progressive　collapse　is　whether　the　frame　beams　can　bear　the　column＇s　load　to　produce　a　new　way　for　transmitting　the　force　or　not.　In　this　paper,　the　simulation　analysis　to　a　six-layer　frame　structure　which　designed　by　the　concrete　structural　design　codes　is　put　up　according　to　the　four　failure　position　of　columns.　The　following　conclusions　are　concluded:　the　damage　in　vertical　region　does　not　appear　or　appear　very　little　because　of　a　strong　stiffness　in　joint　between　invalid　column　and　beam.　Structural　collapse　was　resulted　by　the　collapse　stress　from　displacement　transfering　the　other　end　of　beam　connected　with　columns.