BACKGROUND　Although　aortic　valve　disease　caused　by　left　ventricular　assist　device　(LVAD)　support　has　attracted　more　and　more　attention,　the　precise　biomechanical　effects　of　LVAD　support　level　on　the　aortic　valve　are　still　unclear.　MATERIAL　AND　METHODS　A　structural　finite　element　models　study　was　conducted　using　an　ideal　aortic　valve　geometric　model.　Four　different　study　conditions　were　designed,　according　to　the　reduction　of　the　open　duration　of　the　aortic　valve.　The　isotropic　hyperelastic　constitutive　equation　was　chosen　to　reflect　the　mechanical　property　of　the　leaflets.　The　distribution　of　the　stress,　strain,　and　transient　dynamics　of　the　leaflet　were　calculated.　RESULTS　Along　with　the　increase　of　LVAD　support　level,　the　open　duration　of　the　aortic　valve　was　also　reduced　by　the　increase　of　LVAD　support　(low　support　level　case　0.23　seconds　versus　middle　support　level　case　0.2　seconds　versus　high　support　level　case　0.14　seconds).　Moreover,　along　with　the　increase　of　support　mode　of　LVAD,　the　von　Mises　stress　in　most　leaflet　areas　was　increased　from　the　low　stress　level　(0-0.4　MPa)　to　the　middle　region　(0.4-0.8　MPa).　Once　the　leaflets　were　continuously　closed,　the　high　stress　level　(larger　than　0.8　MPa)　was　observed.　In　contrast,　the　support　level　of　LVAD　only　had　slight　effects　on　the　distribution　of　von　Mises　strain.　According　to　the　aforementioned　results,　maintaining　the　open　duration　of　aortic　valve　longer　than　0.2　seconds　could　achieve　better　performance　of　biomechanical　states　of　leaflets.　CONCLUSIONS　This　study　could　provide　useful　information　on　the　determination　of　optimal　LVAD　support　strategy.