The　wettability　of　the　membrane　surface　has　shown　obvious　influent　on　the　separation　performance　of　the　membrane.　In　this　work,　a　hydrophilic　PDA-[PDDA/TiO2]+　Cl−　membrane　was　prepared　by　a　one-step　codeposition　of　poly(diallyldimethylammonium　chloride)　(PDDA)　polyelectrolyte　solution　containing　positively　charged　TiO2@PDDA　nanoparticles　with　the　assistance　of　dopamine　(DA).　Such　positively　charged　membrane　can　be　transformed　into　a　hydrophobic　membrane　PDA-[PDDA/TiO2]+　PFO−　via　the　counterion　exchange　between　Cl−　and　PFO−　(perfluorooctanoate).　The　transformation　between　hydrophilicity　and　hydrophobicity　is　reversible.　For　both　hydrophilic　and　hydrophobic　membranes,　the　nanofiltration　performances　were　respectively　investigated　by　the　aqueous　solution　and　ethanol　solution　of　dyes　including　methyl　blue　(MB),　Congo　red　(CR)　and　Evans　blue　(EB),　and　as　well　metal　salt　aqueous　solution.　The　consecutive　running　stability　and　anti-fouling　performance　of　both　hydrophilic　and　hydrophobic　membranes　were　explored.　The　results　revealed　that　both　membranes　showed　high　nanofiltration　performances　for　retention　of　dyes　in　(non)aqueous　solution.　For　the　hydrophilic　membrane,　the　rejection　of　salts　in　a　sequence　is　MgSO4　＞　Na2SO4　＞　MgCl2　＞　NaCl.　Moreover,　both　of　the　hydrophilic　and　hydrophobic　membranes　showed　high　stability　and　antifouling　property.　©　2020　Elsevier　B.V.