The　achievement　and　stable　maintenance　of　partial　nitrification　and　partial　anammox　process　for　municipal　sewage　is　a　challenging　research　topic　at　present.　In　this　study,　a　novel　strategy　of　hydroxylamine　(NH2OH)　addition　under　low　DO　condition　was　adopted　for　rapidly　achieving　simultaneous　partial　nitrification　denitrification　and　anammox　process　(SPNDA)　to　deal　with　domestic　wastewater,　the　nitrite　accumulation　ratio　(NAR)　increased　from　1%　to　82%　in　the　first　4　days.　After　the　addition　of　NH2OH　was　stopped,　the　PN　effect　of　SPNDA　process　remained　relatively　stable　within　100　days.　During　the　stable　operation　period　with　aerobic　HRT　of　5　h,　the　nitrogen　removal　efficiency　was　87.9　+/-　4.2%.　Moreover,　the　abundance　of　denitrifying　bacteria　and　Candidatus　Brocadia　increased　from　1.79%　and　0.062%　to　22.49%　and　0.38%　respectively,　which　promoted　nitrogen　removal　effect.　Overall,　this　study　provided　a　quickly　way　for　achieving　the　cost-effective　SPNDA　process　to　enhance　nitrogen　removal　with　NH2OH　addition.