Long-span　air　supported　membrane　structures　are　typical　wind　sensitive　buildings,　wind　load　is　often　their　control　load.　The　existing　analysis　of　air　supported　membrane　structures　basically　assumes　that　the　nodes　of　the　cable　net　and　membrane　are　bound　together,　the　slide　or　separation　between　the　cable　net　and　the　membrane　under　wind　load　is　not　considered.　The　lack　of　cable–membrane　contact　model　causes　hidden　danger　to　the　safety　of　wind　resistance　performance　of　long-span　air　supported　membrane　structures.　In　this　paper,　ANSYS　software　is　adopted　for　structural　analysis,　the　cable　net　of　air　supported　membrane　structure　is　divided　into　many　small　cable　segments,　and　nodes　of　all　cable　segments　form　point-surface　contact　pairs　with　the　membrane　surface,　the　joints　of　all　cable　segments　may　bond,　slide　or　separate　from　the　membrane　surface.　The　cable–membrane　contact　model　is　used　to　analyze　the　wind-induced　response　of　an　air　supported　membrane　structure　with　orthogonal　cable　net,　and　the　results　are　compared　with　the　wind-induced　response　of　the　cable–membrane　binding　model.　The　analysis　results　of　the　two　models　show　that:　when　the　cable–membrane　contact　model　is　adopted,　the　displacement　and　stress　responses　of　the　membrane　are　greatly　increased　under　strong　wind　load　due　to　the　separation　of　the　membrane　and　the　cable　net,　the　axial　force　distribution　of　the　cable　is　more　uniform　due　to　the　sliding　between　the　cable　net　and　membrane.　The　cable–membrane　binding　model　overestimates　the　restraint　effect　of　cable　net　on　membrane,　in　order　to　better　optimize　the　design　of　long-span　air　supported　membrane　structures,　it　is　necessary　to　consider　adopting　cable–membrane　contact　model.　©　2022　Elsevier　Ltd