Objectives:　Infectious　viruses　(e.g.,　SARS-CoV-2,　norovirus)　can　transmit　through　surfaces.　Norovirus　has　infected　millions　of　individuals　annually.　Interventions　on　norovirus　transmission　in　high-risk　indoor　environment　are　important.　Methods:　This　study　focused　on　a　restaurant　in　Guangzhou,　China.　More　than　41,000　touches　by　both　diners　and　staff　members　were　collected　using　video　cameras.　A　surface　transmission　model　was　developed　and　combined　with　these　real　human　touch　behaviors　to　analyze　the　effectiveness　of　different　norovirus　prevention　strategies.　Results:　When　the　virus　carrier　was　a　diner,　the　virus　intake　fraction　of　diners　in　the　same　table　was　the　highest.　Increasing　the　touch　frequency　on　personal　private　surfaces　would　reduce　the　virus　exposure.　The　virus　intake　fraction　was　reduced　by　18.4%　on　average　if　public　surfaces　were　not　touched.　Optimization　on　surface　materials　could　reduce　the　virus　intake　fraction　by　86.6%.　Additionally,　disinfecting　tablecloths,　clothes　of　diners,　and　chairs　were　the　three　most　effective　surface　disinfection　strategies.　Conclusion:　Controlling　human　touch　behavior　(e.g.,　reducing　the　self-touches　on　mucous　membranes)　is　more　effective　than　surface　disinfection　in　controlling　norovirus　transmission,　but　surface　disinfection　cannot　be　ignored　because　human　behavior　is　difficult　to　be　controlled.　©　2022　The　Author(s)