The　use　of　wet　scrubbing　to　remove　airborne　molecular　contaminants　in　cleanroom　make-up　air　units　has　economic　benefits　and　good　application　prospects.　Still,　problems　with　this　method　include　low　removal　efficiency　and　large　water　consumption.　To　improve　scrubbing　performance,　we　built　a　full-scale　scrubbing　experiment　platform　using　SO2　as　the　removal　object.　In　addition,　we　applied　structured　packing　in　the　scrubbing　process　to　enhance　the　mass　transfer　between　gas　and　liquid,　and　we　tested　the　wet　scrubbing　removal　efficiency　and　pressure　drop　under　a　variety　of　operating　conditions.　Results　showed　that　under　the　condition　of　double　-row　spraying　only,　the　SO2　removal　efficiency　increased　with　increasing　liquid-gas　ratio.　The　efficiency　ranged　from　57%　to　83.9%　and　the　pressure　drop　ranged　from　6　to　15　Pa.　After　adding　structured　packing,　the　removal　efficiency　under　different　liquid-gas　ratios　improved　significantly.　Improvement　was　more　apparent,　ranging　from　72.2%　to　86.2%,　when　the　liquid-gas　ratio　was　low.　The　pressure　drop　also　increased,　ranging　between　59　Pa　and　100　Pa.　In　addition,　we　changed　the　packing　thickness　and　the　number　of　stages,　and　found　that　when　the　packing　thickness　was　0.2　m　and　the　two-stage　spacing　was　0.15　m,　removal　efficiency　improved　up　to　89.7%.　The　research　results　are　significant　for　optimizing　wet　scrubbing　performance　and,　at　the　same　time,　have　practical　engineering　value　for　controlling　the　concentration　of　airborne　molecular　contaminants　in　the　cleanrooms.