Ag　is　a　potential　low-cost　oxygen　reduction　reaction(ORR)catalyst　in　alkaline　condition,which　is　important　for　the　zinc-air　batteries.Here,we　report　that　an　Ag　based　single　atom　catalyst　with　heteroatom　coordination.Ag1-h-NPCISC,has　been　synthesized　and　shown　much　improved　performance　towards　ORR　by　manipulating　the　coordination　environment　of　the　Ag　center.It　shows　a　high　half　wave　potential(0.896　V)and　a　high　turnover　frequency(TOF)(5.9　s-1)at　0.85　V,which　are　higher　than　the　previously　reported　Ag　based　catalysts　and　commercial　Pt/C.A　zinc-air　battery　with　high　peak　power　density　of　270　mW·cm-2　is　fabricated　by　using　the　Ag1-h-NPCISC　as　air　electrode.The　high　performance　is　attributed　to(1)the　hollow　structure　providing　good　mass　transfer;(2)the　single　atom　metal　center　structure　providing　high　utility　of　the　Ag;(3)heteroatom　coordination　environment　providing　the　adjusted　binding　to　the　ORR　intermediates.Density　functional　theory(DFT)calculations　show　that　the　energy　barrier　for　the　formation　of　OOH*,which　is　considered　as　the　rate　determine　step　for　ORR　on　Ag　nanoparticles,is　lowered　on　Ag1-h-NPCISC,thus　improving　the　ORR　activity.This　work　demonstrates　that　the　well　manipulated　Ag　based　single　atom　catalysts　are　promising　in　electrocatalysis.