The　human　bone　appears　as　a　hierarchical　structure　composed　of　cortical　bone　with　high　density　and　strength　and　cancellous　bone　with　low　density　and　blood　vessels.　Therefore,　the　structure　and　mechanical　properties　of　human　implants　should　match　the　characteristics　of　human　bone.　Based　on　the　stress　on　the　natural　human　bone,　the　titanium　alloy　porous　structure　designed　by　topology　optimization　method　was　fabricated　by　laser　powder　bed　fusion　(LBPF).　The　mechanical　properties　and　deformation　failure　mode　of　the　porous　structure　were　analyzed　by　compression　experiment　and　numerical　simulation.　It　was　found　that　the　numerical　simulation　and　experimental　results　have　a　high　consistency　in　the　current　work.　Finally,　by　comparing　with　the　mechanical　properties　of　human　natural　bone,　combined　with　the　failure　mode　of　porous　structure,　a　porous　material　suitable　for　human　implants　was　obtained.