The　rapid　urbanization　and　industrialization　in　the　coastal　Zhuhai　have　resulted　in　severe　heavy　metal　contamination.　Heavy　metals　are　extensively　used　as　indicators　of　coastal　contamination,　but　the　comparability　among　different　geographic　environments　needs　to　be　further　explored　and　scrutinized.　In　this　study,　heavy　metals　(i.e.,　As,　Zn,　Cd,　Cr,　Hg,　Cu,　and　Pb)　in　surface　seawater　(20　sites),　sediments　(10　sites),　and　organisms　(13　sites,　shellfish,　algae,　fish,　and　crustaceans)　were　analyzed　to　assess　the　distribution,　enrichment,　and　ecological　risk　in　the　coastal　regions　of　Zhuhai　(2017　and　2018).　The　results　showed　that　Cu,　Zn,　and　Pb　exceeded　the　standards　of　seawater,　indicating　the　presence　of　anthropogenic　pollution.　Meanwhile,　the　ecological　risk　results　showed　that　Cd　and　Cu　indicated　moderately　high　environmental　risks.　The　quantity　and　quality　of　heavy　metals　in　organisms　showed　different　trends　in　the　sea,　which　affected　marine　organisms　in　the　northeastern　area.　The　main　factors　contributing　to　the　ecological　risk　of　these　two　heavy　metals　are　the　emissions　from　chemical　companies.　Therefore,　preserving　the　high　biological　diversity　in　this　area　is　important　to　ensure　the　health　and　productivity　of　the　seawater　ecosystem　in　the　coastal　area.　These　results　may　play　a　key　role　in　promoting　decision　makers　to　manage　the　sustainability　of　the　Zhuhai　coast.