Bacterial　infections　have　threatened　human　health　significantly　due　to　the　misuse　of　antibiotics　and　iterations　of　multi-drug-resistant　bacteria.　Inorganic　antimicrobial　ZnO　agents　can　effectively　solve　the　bacterial　drug　resistance　and　play　an　important　role　as　commonly　used　photocatalysts　in　the　fields　of　antibacterial,　water　purification,　and　air　purification.　Herein,　graphene　oxide　(GO)　modified　ZnO　microtubular　composite　photocatalytic　antimicrobial　agents　(PAA)　were　fabricated　via　the　optical　vapor　phase　supersaturation　and　drop-spraying　method,　by　which　the　photocatalytic　activity　was　boosted　and　achieved　more　than　98%　antimicrobial　activity　against　Escherichia　coli　and　Staphylococcus　aureus　under　sunlight　irradiation.　The　ZnO/GO　PAA　can　further　combine　with　a　polypropylene-based　photo-catalytic　filter　for　high　antibacterial　activity,　rapid　sterilization,　and　well　reusability.　Under　a　UV　irradiation　of　similar　to　150　s,　the　antibacterial　efficiency　of　a　filter　modified　facial　mask　(F-Mask)　degrades　particles　and　bacteria　up　to　100%.　The　photocatalytic　antibacterial　F-Mask　exhibits　outstanding　mechanical　flexibility　for　over　300　bending　cycles.　This　work　provides　a　platform　for　the　design　of　antibacterial　filter　materials　to　alleviate　the　social　epidemic　prevention　pressure　during　the　period　of　large-scale　epidemics.