Veterinary　antibiotics　in　swine　wastewater　has　drawn　great　public　attention.　The　removal　processes　of　sulfamethizole　(SMZ),　enrofloxacin　(ENR)　and　chlortetracycline　(CTC)　were　investigated　in　the　high-rate　anaerobic　process.　The　continuous　experiments　demonstrated　that　in　3　L　working　volume　and　with　the　organic　loading　rate　5　kg/(m(3)center　dot　d)　rised　to　20　kg/(m(3)center　dot　d),　the　average　removal　efficiencies　of　the　high-rate　anaerobic　bioreactor　for　SMZ,　ENR　and　CTC　were　0,　54　and　100%,　respectively.　By　using　fixed-bed　adsorption　models,　the　saturation　time　of　SMZ,　ENR　and　CTC　were　4　hydraulic　retention　time　(HRT)　(24　h),　8　HRT　(48　h)　and　372　HRT　(2,232　h).　In　the　batch　experiments,　the　adsorption　and　biodegradation　characteristics　of　anaerobic　granular　sludge　were　determined.　In　the　high-rate　anaerobic　bioreactor,　SMZ　removal　process　mainly　relied　on　the　adsorption　but　it　was　very　weak;　ENR　removal　process　was　based　on　the　adsorption　and　biodegradation;　CTC　removal　process　was　based　to　a　large　extent　on　the　adsorption　because　of　the　big　capacity　of　AnGS.　These　results　were　helpful　to　create　a　rational　basis　for　designing　more　suitable　treatment　systems　as　feasible　barriers　to　the　release　of　antibiotics　into　the　environment.