Groundwater　pollution　in　karst　areas　is　often　the　result　of　the　interaction　of　hydrogeological　characteristics　and　human　activities.　In　this　study,　a　chimeric　evaluation　system　of　groundwater　vulnerability　and　pollution　load　was　constructed,　and　the　groundwater　contamination　risk　was　intuitively　displayed　using　a　risk　map.　The　study　area　is　located　in　Qiannan,　a　typical　karst　area　in　Southwest　China.　Groundwater　vulnerability　was　mainly　calculated　using　the　PLEIK　model.　Pollution　source　load　evaluation　was　evaluated　using　the　classification　method.　The　groundwater　pollution　status　was　evaluated　by　the　CCME　WQI　method.　The　results　show　that　the　groundwater　vulnerability　in　the　research　area　was　mainly　at　a　medium　level.　The　areas　with　high　pollution　load　values　were　mainly　distributed　in　industrial　parks　and　other　pollution-source-gathering　areas.　The　results　of　the　water　quality　evaluation　show　that　the　groundwater　quality　in　the　study　area　was　generally　good.　However,　the　impact　of　some　pollution　sources　on　the　surrounding　groundwater　still　cannot　be　ignored.　The　results　reveal　the　risk　level　of　groundwater　pollution　in　typical　karst　areas　and　provide　theoretical　support　for　regional　groundwater　protection.