Cache　prefetching　is　a　traditional　way　to　reduce　memory　access　latency.　In　multi-core　systems,　aggressive　prefetching　may　harm　the　system.　In　the　past,　prefetching　throttling　strategies　usually　set　thresholds　through　certain　factors.　When　the　threshold　is　exceeded,　prefetch　throttling　strategies　will　control　the　aggressive　prefetcher.　However,　these　strategies　usually　work　well　in　homogeneous　multi-core　systems　and　do　not　work　well　in　heterogeneous　multi-core　systems.　This　paper　considers　the　performance　difference　between　cores　under　the　asymmetric　multi-core　architecture.　Through　the　improved　hill-climbing　method,　the　aggressiveness　of　prefetching　for　different　cores　is　controlled,　and　the　IPC　of　the　core　is　improved.　Through　experiments,　it　is　found　that　compared　with　the　previous　strategy,　the　average　performance　of　big　core　is　improved　by　more　than　3%,　and　the　average　performance　of　little　cores　is　improved　by　more　than　24%.　©　2023,　The　Author(s).