As　a　national　pilot　city　for　solid　waste　disposal　and　resource　reuse,　Dongguan　in　Guangdong　Province　aims　to　vigorously　promote　the　high-value　utilization　of　solid　waste　and　contribute　to　the　sustainable　development　of　the　Greater　Bay　Area.　In　this　study,　life　cycle　assessment　(LCA)　coupled　with　principal　component　analysis　(PCA)　and　the　random　forest　(RF)　algorithm　was　applied　to　assess　the　environmental　impact　of　multi-source　solid　waste　disposal　technologies　to　guide　the　environmental　protection　direction.　In　order　to　improve　the　technical　efficiency　and　reduce　pollution　emissions,　some　advanced　technologies　including　carbothermal　reduction‒oxygen-enriched　side　blowing,　directional　depolymerization‒flocculation　demulsification,　anaerobic　digestion　and　incineration　power　generation,　were　applied　for　treating　inorganic　waste,　organic　waste,　kitchen　waste　and　household　waste　in　the　park.　Based　on　the　improved　techniques,　we　proposed　a　cyclic　model　for　multi-source　solid　waste　disposal.　Results　of　the　combined　LCA-PCA-RF　calculation　indicated　that　the　key　environmental　load　type　was　human　toxicity　potential　(HTP),　came　from　the　technical　units　of　carbothermal　reduction　and　oxygen-enriched　side　blowing.　Compared　to　the　improved　one,　the　cyclic　model　was　proved　to　reduce　material　and　energy　inputs　by　66%–85%　and　the　pollution　emissions　by　15%–88%.　To　sum　up,　the　environmental　impact　assessment　and　systematic　comparison　suggest　a　cyclic　mode　for　multi-source　solid　waste　treatments　in　the　park,　which　could　be　promoted　and　contributed　to　the　green　and　low-carbon　development　of　the　city.　©　2023