In　order　to　study　the　setting　effect　of　highway　tunnel　facade　marking,　based　on　human　factor　engineering,　driving　simulation　technology　was　used　to　build　a　tunnel　simulation　scene　to　explore　the　influence　of　different　facade　marking　settings　on　the　edge　of　the　tunnel　maintenance　road　on　the　driver.　This　paper　analyzes　the　average　speed,　acceleration,　lateral　placement,　throttle　power,　pupil　area,　and　other　indicators　under　different　facade　marking　schemes,　and　uses　ETEW　to　analyze　the　feasibility　of　different　facade　marking　schemes　from　the　perspective　of　driving　safety,　stability,　and　comfort.　The　results　show　that　the　facade　marking　on　the　edge　of　the　tunnel　maintenance　road　is　better　than　the　basic　tunnel　facilities　scheme,　the　whole　yellow　part　of　the　tunnel　curve　section　is　the　optimal　scheme,　and　the　black　and　yellow　part　of　the　middle　section　of　the　tunnel　is　the　optimal　scheme.　©　2020　ASCE.