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Author:

Liu, N. (Liu, N..) | Hou, Q. (Hou, Q..) | Liu, S. (Liu, S..) | Li, X. (Li, X..) | Pan, Y. (Pan, Y..) | Qiao, A. (Qiao, A..)

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Scopus

Abstract:

Objective: To explore the biomechanical mechanism of aortic insufficiency (AI) after single aortic valve replacement (SAVR) in children and propose the corresponding countermeasures. Methods: The idealized aortic valve model and postoperative growth model were constructed. By changing the length of leaflet free edge, leaflet height as well as improving the design with a concave structure, the effects of different structure dimensions on movement synchronization and closing performance of the aortic valve after surgery were compared. Results: The closure of the replacement leaflet lagged behind the autologous leaflet, which fitted 2 mm below free edge of the replacement leaflet. AI occurred 6 years after operation. Increasing leaflet height could not improve the postoperative effect and would increase the maximum stress of the leaflet. Increasing free edge length by 10% could improve the postoperative outcomes, while increasing free edge length by 15% would cause the leaflet to be too long, hence resulting in a poor fit of the aortic valve. Compared with the traditional structure, the concave structure was more beneficial for closing performance of the aortic valve, and it could effectively reduce the maximum stress by 20% with the best effect. Conclusions: The leaflet movement will be out of synchronization after SAVR, the point of convergence will be shifted, and AI will appear 6 years after surgery. It is recommended to use a concave structure with free edge length increased by 10%, while increasing leaflet height is not recommended. Copyright © 2021 by the Editorial Board of Journal of Medical Biomechanics.

Keyword:

Numerical simulation Aortic valve replacement Aortic insufficiency Single valve replacement

Author Community:

  • [ 1 ] [Liu N.]Faculty of Environment and Life, Beijing University of Technology, Beijing, 100124, China
  • [ 2 ] [Liu N.]Intelligent Physiological Measurement and Clinical Translation, Beijing International Base for Scientific and Technological Cooperation, Beijing, 100124, China
  • [ 3 ] [Hou Q.]Faculty of Environment and Life, Beijing University of Technology, Beijing, 100124, China
  • [ 4 ] [Hou Q.]Intelligent Physiological Measurement and Clinical Translation, Beijing International Base for Scientific and Technological Cooperation, Beijing, 100124, China
  • [ 5 ] [Liu S.]Faculty of Environment and Life, Beijing University of Technology, Beijing, 100124, China
  • [ 6 ] [Liu S.]Intelligent Physiological Measurement and Clinical Translation, Beijing International Base for Scientific and Technological Cooperation, Beijing, 100124, China
  • [ 7 ] [Li X.]Faculty of Environment and Life, Beijing University of Technology, Beijing, 100124, China
  • [ 8 ] [Li X.]Intelligent Physiological Measurement and Clinical Translation, Beijing International Base for Scientific and Technological Cooperation, Beijing, 100124, China
  • [ 9 ] [Pan Y.]Faculty of Environment and Life, Beijing University of Technology, Beijing, 100124, China
  • [ 10 ] [Pan Y.]Intelligent Physiological Measurement and Clinical Translation, Beijing International Base for Scientific and Technological Cooperation, Beijing, 100124, China
  • [ 11 ] [Qiao A.]Faculty of Environment and Life, Beijing University of Technology, Beijing, 100124, China
  • [ 12 ] [Qiao A.]Intelligent Physiological Measurement and Clinical Translation, Beijing International Base for Scientific and Technological Cooperation, Beijing, 100124, China

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Source :

Journal of Medical Biomechanics

ISSN: 1004-7220

Year: 2021

Issue: 6

Volume: 36

Page: 869-876

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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