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Author:

Mao, Boyan (Mao, Boyan.) | Feng, Yue (Feng, Yue.) | Wang, Wenxin (Wang, Wenxin.) | Li, Bao (Li, Bao.) | Zhao, Zhou (Zhao, Zhou.) | Zhang, Xiaoyan (Zhang, Xiaoyan.) | Jin, Chunbo (Jin, Chunbo.) | Wu, Dandan (Wu, Dandan.) | Liu, Youjun (Liu, Youjun.) (Scholars:刘有军)

Indexed by:

EI Scopus SCIE PubMed

Abstract:

In the existing patency prediction model of coronary artery bypass grafting (CABG), the characteristics are based on graft flow, but no researchers selected hemodynamic factors as the characteristics. The purpose of this paper is to study whether the introduction of hemodynamic factors will affect the performance of the prediction model. Transit time flow-meter (TTFM) waveforms and 1-year postoperative patency results were obtained from 50 internal mammary arterial grafts (LIMA) and 82 saphenous venous grafts (SVG) in 60 patients. Taking TTFM waveforms as the boundary conditions, the CABG ideal models were constructed to obtain hemodynamic factors in grafts. Based on clinical characteristics and combination of clinical and hemodynamic characteristics, patency prediction models based on support vector machine (SVM) were constructed respectively. For LIMA, after the introduction of hemodynamic factors, the accuracy, sensitivity and specificity of the prediction model increased from 70.35%, 50% and 74.17% to 78.02%, 70% and 78.89%, respectively. For SVG, the accuracy, sensitivity and specificity of the prediction model increased from 63.24%, 40% and 76.91% to 74.41%, 60.1% and 82.73%, respectively. The performance of the prediction model can be improved by introducing hemodynamic factors into the characteristics of the model. The accuracy, sensitivity and specificity of the prediction results are higher with the addition of hemodynamic characteristics. (C) 2019 Elsevier Ltd. All rights reserved.

Keyword:

Support vector machine Transit time flow-meter Hemodynamics Coronary artery bypass grafting Graft patency

Author Community:

  • [ 1 ] [Mao, Boyan]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 Pingleyuan, Beijing 100124, Peoples R China
  • [ 2 ] [Feng, Yue]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 Pingleyuan, Beijing 100124, Peoples R China
  • [ 3 ] [Wang, Wenxin]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 Pingleyuan, Beijing 100124, Peoples R China
  • [ 4 ] [Li, Bao]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 Pingleyuan, Beijing 100124, Peoples R China
  • [ 5 ] [Zhang, Xiaoyan]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 Pingleyuan, Beijing 100124, Peoples R China
  • [ 6 ] [Jin, Chunbo]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 Pingleyuan, Beijing 100124, Peoples R China
  • [ 7 ] [Wu, Dandan]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 Pingleyuan, Beijing 100124, Peoples R China
  • [ 8 ] [Liu, Youjun]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 Pingleyuan, Beijing 100124, Peoples R China
  • [ 9 ] [Zhao, Zhou]Peking Univ, Cardiac Surg Dept, Peoples Hosp, 11th South Ave, Beijing, Peoples R China
  • [ 10 ] [Wang, Wenxin]Neusoft Beijing R&D Ctr, Neusoft Med Syst, Zhongguancun Software Pk 10,Xibeiwang East Rd, Beijing 100194, Peoples R China

Reprint Author's Address:

  • 刘有军

    [Liu, Youjun]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 Pingleyuan, Beijing 100124, Peoples R China

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Source :

JOURNAL OF BIOMECHANICS

ISSN: 0021-9290

Year: 2020

Volume: 98

2 . 4 0 0

JCR@2022

ESI Discipline: MOLECULAR BIOLOGY & GENETICS;

ESI HC Threshold:219

Cited Count:

WoS CC Cited Count: 7

SCOPUS Cited Count: 10

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 8

Online/Total:1797/10900887
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