The　gradient　distribution　of　platinum　loading　in　the　catalyst　layer　along　the　flow　channel　direction　affects　the　utilization　of　reactants　and　the　transfer　of　heat　and　species.　On　this　basis,　the　influence　of　operating　conditions　on　the　cell　performance,　heat　and　mass　transfer　of　proton　exchange　membrane　fuel　cells　with　platinum　loading　gradient　distribution　along　the　flow　channel　direction　is　still　unclear.　Therefore,　based　on　a　two-dimensional,　non-isothermal,　two-phase　proton　exchange　membrane　fuel　cell　model,　the　effects　of　reactants　flow　direction　and　stoichiometric　ratio　on　proton　exchange　membrane　fuel　cells　with　the　two-gradient　distribution　or　the　three-gradient　distribution　of　platinum　loading　in　the　multi-gradient　distributions　were　investigated.　The　results　show　that　the　reactant　flow　direction　has　a　weak　impact　on　the　electrical　performance　and　species　content　of　platinum　loading　gradient　distribution　fuel　cells　and　the　increase　of　stoichiometric　ratio　can　improve　the　performance　of　the　fuel　cell　with　platinum　loading　gradient　distribution.　Furthermore,　with　the　increase　of　stoichiometric　ratio,　the　performance　improvement　degree　of　the　cell　with　gradient　distribution　of　platinum　loading　increases　compared　with　the　uniform　distribution.　©　2023　Chemical　Industry　Press.　All　rights　reserved.