Tunnel　slope　is　an　important　factor　affecting　smoke　spreading　for　a　stopped　subway　train　on　fire.　In　this　paper,　a　multi-scale　method　where　one-dimensional　(1D)　network　is　coupled　with　three-dimensional　(3D)　field　simulation　is　used　to　calculate　smoke　and　temperature　distributions　for　a　fire　occurred　in　the　middle　part　of　the　subway　train　in　tunnel.　The　tunnel　slopes　of　0‰,　12‰,　21‰　and　30‰　are　considered.　By　comparing　the　temperature　distribution　in　a　condition　with　natural　ventilation　and　with　2　m/s　longitudinal　ventilation,　we　comprehensively　analyzed　temperature,　smoke　spread　characteristics.　Results　show　that　tunnel　slope　has　a　great　influence　on　temperature　and　smoke　profile　when　slope　is　higher　than　12‰.　The　temperature　at　1.8m　would　exceed　the　safe　limit　of　60°C　at　60　s　after　fire　ignition.　The　larger　the　slope,　the　higher　temperature　would　be　in　the　train　carriage.　For　a　train　fire　scenario　with　natural　ventilation,　within　initial　120　s　period　the　train　compartment　could　keep　a　safe　evacuation　condition.　This　research　would　provide　reference　for　making　right　evacuation　plan　of　subway　tunnel　fire.