Subway　systems　are　a　crucial　component　of　urban　public　transportation,　especially　in　terms　of　safety　during　seismic　events.　Soil　liquefaction　triggered　by　earthquakes　is　one　of　the　key　factors　that　can　lead　to　underground　structural　damage.　This　study　investigates　the　impact　of　deep　soil　liquefaction　on　the　response　of　subway　station　structures　during　seismic　activity,　aiming　to　provide　evidence　and　suggestions　for　earthquake-resistant　measures　in　underground　constructions.　The　advanced　finite　element　software　PLAXIS　was　utilized　for　dynamic　numerical　simulations.　Non-linear　dynamic　analysis　methods　were　employed　to　construct　models　of　subway　stations　and　the　surrounding　soil　layers,　including　soil-structure　interactions.　The　UBC3D-PLM　liquefaction　constitutive　model　was　applied　to　describe　the　liquefaction　behavior　of　soil　layers,　while　the　HS　constitutive　model　was　used　to　depict　the　dynamic　characteristics　of　non-liquefied　soil　layers.　The　study　examined　the　influence　of　deep　soil　liquefaction　on　the　dynamic　response　of　subway　station　structures　under　different　seismic　waves.　The　findings　indicate　that　deep　soil　liquefaction　significantly　increases　the　vertical　displacement　and　acceleration　responses　of　subway　stations　compared　to　non-liquefied　conditions.　The　liquefaction　behavior　of　deep　soil　layers　leads　to　increased　horizontal　effective　stress　on　both　sides　of　the　structure,　thereby　increasing　the　horizontal　deformation　of　the　structure　and　posing　a　potential　threat　to　the　safety　and　functionality　of　subway　stations.　This　research　employed　detailed　numerical　simulation　methods,　incorporating　the　non-linear　characteristics　of　deep　soil　layer　liquefaction,　providing　an　analytical　framework　based　on　regulatory　standards　for　evaluating　the　impact　of　deep　soil　liquefaction　on　the　seismic　responses　of　subway　stations.　Compared　to　traditional　studies,　this　paper　significantly　enhances　simulation　precision　and　practical　applicability.　Results　from　this　research　indicate　that　deep　soil　layer　liquefaction　poses　a　non-negligible　risk　to　the　structural　safety　of　subway　stations　during　earthquakes.　Therefore,　the　issue　of　deep　soil　liquefaction　should　receive　increased　attention　in　engineering　design　and　construction,　with　effective　prevention　and　mitigation　measures　being　implemented.