The　advancement　of　artificial　intelligence　(AI)　and　the　ubiquity　of　social　media　have　become　transformative　agents　in　contemporary　educational　ecosystems.　The　spotlight　of　this　inquiry　focuses　on　the　nexus　between　AI　and　social　media　usage　in　relation　to　academic　performance　and　mental　well-being,　and　the　role　of　smart　learning　in　facilitating　these　relationships.　Using　partial　least　squares–structural　equation　modeling　(PLS-SEM)　on　a　sample　of　401　Chinese　university　students.　The　study　results　reveal　that　both　AI　and　social　media　have　a　positive　impact　on　academic　performance　and　mental　well-being　among　university　students.　Furthermore,　smart　learning　serves　as　a　positive　mediating　variable,　amplifying　the　beneficial　effects　of　AI　and　social　media　on　both　academic　performance　and　mental　well-being.　These　revelations　contribute　to　the　discourse　on　technology-enhanced　education,　showing　that　embracing　AI　and　social　media　can　have　a　positive　impact　on　student　performance　and　well-being.　©　2024