Inorganic　scintillators　play　a　pivotal　role　in　diverse　fields　like　medical　imaging,　nondestructive　detection,　homeland　security,　and　high-energy　physics.　However,　traditional　inorganic　scintillators　encounter　challenges　such　as　high　fabrication　costs　and　low　light　yield.　Recently,　low-dimensional　metal　halide　scintillators　(LDMHS)　have　witnessed　rapid　progress,　owing　to　their　distinctive　crystal　structure　and　superior　radioluminescence　performance.　Herein,　an　overview　of　recent　advancements　and　proposed　instructive　pathways　for　achieving　high-performance　LDMHS　is　provided.　First,　the　scintillation　physical　mechanism　and　emphasis　on　the　essential　requirements　of　scintillators　for　diverse　applications　are　elucidated.　Furthermore,　LDMHS　by　the　B-site,　introducing　recent　advancements　and　providing　insights　into　their　characteristics　is　categorized.　This　encompasses　the　understanding　of　structure-property　relationships　and　the　routes　and　rules　for　optimizing　scintillation　performance.　Finally,　the　persisting　challenges　in　this　burgeoning　field　and　proposed　potential　research　directions　for　future　exploration　are　discussed.　©　2024　Wiley-VCH　GmbH.