Solid　oxide　fuel　cells　(SOFCs)　are　an　effective　and　sustainable　energy　conversion　technology.　As　operating　temperatures　decrease,　metal　interconnects　and　supports　are　widely　employed　in　SOFCs.　It　is　critical　to　apply　a　protective　coat　on　ferritic　stainless　steel　(FSS)　to　suppress　Cr　evaporation　and　element　interdiffusion　under　high　temperatures.　Electrophoretic　deposition　(EPD)　is　a　promising　approach　for　depositing　metal　oxides　on　FSS　substrate.　Here,　a　method　based　on　3D　multi-physical　simulation　and　orthogonal　experimental　design　was　proposed　to　optimize　deposition　parameters,　including　applied　voltage,　deposition　time,　and　electrode　distance.　The　EPD　process　to　deposit　Mn1.5Co1.5O4　particles　in　a　suspension　of　ethanol　and　isopropanol　was　simulated　and　the　effects　of　these　three　factors　on　the　film　thickness　and　uniformity　were　analyzed.　The　results　indicate　that　applied　voltage　has　the　greatest　impact　on　deposition　thickness,　followed　by　deposition　time　and　electrode　distance.　Meanwhile,　deposition　time　exhibits　a　more　significant　effect　on　film　unevenness　than　applied　voltage.　Additionally,　the　particle-fluid　coupling　phenomenon　was　analyzed　during　the　EPD　process.　In　practice,　these　deposition　parameters　must　be　selected　appropriately　and　the　deposition　time　must　be　controlled　to　obtain　a　uniform　coating.　The　proposed　method　can　reduce　cost　and　shorten　the　design　period.