Currently,　the　district　heating　system　in　northern　China　primarily　employs　two　types　of　terminals,　namely　radiators　and　radiant　floors.　The　heating　design　temperature　is　set　for　the　center　of　the　room　without　considering　local　thermal　comfort　for　individuals.　As　the　real　thermal　environment　within　buildings　is　non-uniform,　variations　in　thermal　sensation　across　different　parts　of　the　body　will　affect　whole-body　thermal　comfort.　Therefore,　it　is　crucial　to　prioritize　local　thermal　comfort　when　setting　room　temperatures　for　heating　purposes.　In　this　study,　we　analyzed　the　data　from　the　chamber　experiments　and　Chinese　Thermal　Comfort　Database,　focusing　on　the　district　heating　environments　of　residences,　office　buildings,　and　university　classrooms　in　severe　cold　and　cold　zones.　We　developed　a　thermal　sensation　evaluation　model　for　analyzing　the　most　uncomfortable　body　part,　investigated　the　lower　limit　of　acceptable　air　temperature　for　this　specific　body　part　and　inferred　appropriate　setpoint　based　on　both　this　limit　and　head-ankle　temperature　difference.　The　results　indicate　that　ankles　are　the　most　uncomfortable　part　with　an　estimated　lower　limit　of　acceptable　air　temperature　at　approximately　18　degrees　C.　Consequently,　we　recommend　setting　room　temperatures　of　20　degrees　C　for　radiator　heating　(RH)　and　19　degrees　C　for　floor　heating　(FH)　to　ensure　ankle　thermal　comfort.　The　findings　of　this　study　can　provide　theoretical　basis　for　reasonable　settings　of　heating　room　temperature　for　the　aforementioned　three　types　of　buildings　in　northern　China,　thereby　further　achieving　energy　conservation.