Over　recent　years,　economic　development　and　environmental　degradation　have　become　major　challenges　that　pressurize　organizations　to　adopt　a　green　innovation　culture.　Therefore,　green　human　resource　management　(GHRM)　practices　are　necessary　to　improve　sustainable　performance　in　healthcare　organizations　functioning　in　Pakistan.　This　study　literature　on　GHRM　practices　with　green　innovation　supports　an　environment-friendly　atmosphere　in　the　business　world　to　achieve　sustainable　performance.　At　the　same　time,　managing　risk　remains　limited　in　the　health　sector.　Therefore,　the　present　study　intends　to　identify　the　execution　of　GHRM　practices　through　green　innovation　on　sustainable　performance　in　healthcare　organizations.　Additionally,　this　study　evaluates　the　moderating　effect　of　risk　management　among　green　innovation　and　GHRM　practices　toward　sustainable　performance.　This　study　scrutinizes　the　following　relationships　from　a　sample　of　400　respondents　from　Pakistan’s　government　and　non-government　hospitals.　The　partial　least　structure　equation　modeling　method　(PLS-SEM)　is　implemented　to　measure　the　structural　framework　of　sustainable　performance.　Results　showed　that　GHRM　practices　positively　affect　sustainable　performance　through　green　innovation.　Additionally,　risk　management　significantly　moderates　the　relationship　between　GHRM　practices　and　green　innovation　towards　sustainable　performance.　However,　GHRM　practices　in　an　eco-friendly　environment　have　meaningful　directions　for　top　managers　and　policy-makers　of　healthcare　organizations　to　develop　a　green　innovation　culture　to　mitigate　the　risk　and　boost　sustainable　performance.　©　2024　The　Author(s).　Published　by　Informa　UK　Limited,　trading　as　Taylor　&　Francis　Group.