The　pancreas　is　adjacent　to　critical　organs;　excessive　microwave　ablation　(MWA)　can　result　in　serious　complications.　The　purpose　of　this　paper　is　to　provide　the　reference　data　of　pancreas　MWA　for　clinicians,　analyze　the　ablation　outcomes　under　different　ablation　parameters,　and　determine　the　critical　temperature　of　pancreatic　surface　fat　liquefaction　outflow.　Combinations　of　two　power　levels　(30　W　and　55　W),　three　antenna　diameters　(1.3　mm,　1.6　mm,　and　1.9　mm),　and　three　ablation　times　(1　min,　1.5　min,　and　2　min)　were　applied　to　an　ex　vivo　pig　pancreas.　Temperature　measurements　were　taken　at　four　thermocouple　points.　The　center　point　is　located　5　mm　horizontally　from　the　antenna　slot,　with　a　temperature　measurement　point　located　5　mm　above,　below,　and　to　the　right　of　the　center　point.　Main　effect　analysis　and　variance　analysis　were　used　to　quantify　the　influences　of　each　factor　on　the　ablation　outcomes.　At　30　W,　the　antenna　diameter　contributing　the　most　at　48.5%.　At　30　W-1.3　mm-1　min,　the　spherical　index　(1.41)　is　closest　to　1.　At　55　W,　the　coagulation　zone　size　was　almost　only　affected　by　the　ablation　time,　with　a　contribution　rate　of　28.7%,　the　temperature　at　point　C　exceeds　point　B.　On　the　surface　of　the　ex　vivo　porcine　pancreas,　the　fat　outflow　temperature　was　54　&　atilde;.　Ablation　combinations　with　low　power,　short　duration,　and　small　antenna　diameter　results　in　a　more　nearly　spherical　coagulation　zone.　When　performing　MWA　on　the　pancreas,　it　is　advisable　to　avoid　areas　with　higher　fat　content,　while　keeping　the　pancreatic　surface　temperature　below　54　degrees　C.