Ordered　metal　nanoparticle　arrays　have　attracted　considerable　attention　as　promising　substrates　for　surface-enhanced　Raman　spectroscopy　owing　to　their　dense　and　homogeneous　distribution　of　＂hot　spots＂.　However,　achieving　uniformity　and　stability　in　these　structures　remains　challenging.　In　this　study,　we　fabricated　an　Ag　nanoparticle　array　(NPA)/monolayer　MoS2　hybrid　using　an　anodized　aluminum　template　and　a　wet　transfer　method.　The　Ag　NPA/MoS2　hybrid,　after　annealing　at　290　degrees　C,　displayed　exceptional　sensitivity　in　detecting　rhodamine　6G　at　concentrations　as　low　as　10(-12)　M.　This　enhancement　can　be　attributed　to　the　enhanced　coupling　effect　between　the　Ag　nanoparticle　arrays　and　MoS2,　alongside　the　optimization　of　the　Ag　nanoparticle　morphology.　Moreover,　the　hybrid　substrate　annealed　at　290　degrees　C　demonstrated　outstanding　reproducibility　in　both　point-to-point　and　substrate-to-substrate　measurements,　with　relative　standard　deviations　of　5.39　and　7.24%,　respectively.　These　findings　highlight　the　potential　of　the　Ag　NPA/MoS2　hybrid　for　trace　detection　applications　in　food　and　environmental　safety.