Reasonable　capture　of　the　chemo-mechanical　damage　evolution　of　concrete　is　of　great　significance　for　predicting　the　service　performance　of　structures.　This　paper　conducts　cyclic　loading　tests　to　investigate　the　evolution　of　strength,　stiffness,　deformation,　and　energy　in　concrete　subjected　to　the　coupled　actions　of　sulfate　attack　environment　and　load.　The　experimental　results　indicate　that　sulfate-attacked　concrete　undergoes　more　significant　performance　degradation　compared　with　unexposed　specimens.　Additionally,　the　analysis　of　dissipated　energy　reveals　different　crack　evolution　of　concrete　under　various　exposure　conditions,　with　through-cracks　forming　in　sulfate-attacked　specimens.　Based　on　the　analysis　of　damage　mechanisms,　a　general　formulation　chemomechanical　coupling　damage　variable　is　given.　The　sulfate　attack-induced　damage　and　the　stress-induced　damage　are　captured　by　the　proposed　chemical　and　mechanical　damage　variables,　respectively.　The　capability　of　the　proposed　damage　variables　is　verified　by　comparing　the　experimental　data　with　the　theoretical　curves.