The　monitoring　of　biophysical　signal　parameters,　including　respiration,　heartbeat,　and　fetal　movement　(FM),　is　essential　for　disease　prevention　and　diagnosis.　In　this　article,　to　achieve　long-term　monitoring　of　biophysical　signals,　a　high-sensitivity　flexible　capacitive　sensor　(FCS)　based　on　carbon　nanotube　(CNT)-filled　dielectric　composite　(DC)　with　multilayer　pore　architecture　is　designed　and　fabricated,　where　the　exquisite　structure　of　DC　is　constructed　based　upon　the　characteristics　of　low　surface　vapor　pressure　of　1,2-propanediol　(1,2-PG)　and　3-D　printing　technology　(3-D-p),　while　the　electrode　material　has　consisted　of　conductive　silicone　rubber　(CSR)　filled　with　silver-coated　glass　fiber　(AGF).　The　fabricated　sensor　exhibits　a　low　detection　limit　(12　Pa),　a　high　sensitivity　in　a　wide　range　(2.3　kPa(　-1)　to　pressure　load　less　than　1.5　kPa,　and　0.73　kPa(　-1)　to　the　pressure　between　1.5　and　12.5　kPa),　fast　response　time　(0.3　s),　and　excellent　stability　(　＞10(4)　cycles).　Numerical　simulation　and　mechanism　analysis　indicate　that　the　varying　dielectric　constant　of　CNT-filled　DC　with　pressure　is　the　key　to　high　sensitivity　for　the　sensor,　and　the　pore　architecture　enlarges　the　load　response　range.　The　FCS　is　sensitive　enough　to　capture　simultaneously　multiple　signals　of　subtle　movements,　including　breathing,　heartbeat,　and　skin　touching　in　the　abdomen,　which　could　be　distinguished　with　the　help　of　post-digital　analysis.　It　is　foreseeable　that　the　sensor　has　a　broad　perspective　application　in　the　field　of　biophysical　signal　monitoring　in-home　or　medical　electronic　healthcare.