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Author:

Li, Yujie (Li, Yujie.) | Anzai, Hitomi (Anzai, Hitomi.) | Nakayama, Toshio (Nakayama, Toshio.) | Shimizu, Yasumoto (Shimizu, Yasumoto.) | Miura, Yukihisa (Miura, Yukihisa.) | Qiao, Aike (Qiao, Aike.) (Scholars:乔爱科) | Ohta, Makoto (Ohta, Makoto.)

Indexed by:

EI Scopus

Abstract:

In previous published research, the deployment of flow-diversion increases the intra-aneurysmal pressure by 20 mmHg in the case with a pre-aneurysm stenosis. The purpose of this study is to learn the influence to the aneurysm when a pre-aneurysm stenosis exists which may threaten people's health even more severely. In the present research, idealized models of straight and curved blood vessels with both aneurysm and pre-aneurysm stenosis were established, with altering the degree of stenosis, the distance between stenosis and aneurysm and the curvature of parent artery. As the degree of stenosis increases, the reattachment length increases in straight vessels. Different positions of reattachment points to aneurysm neck affect the flow pattern inside the aneurysm. In the model with higher degree of stenosis and smaller distance between stenosis and aneurysm, the flow pattern and the direction of vortexes inside the aneurysm are affected by the recirculation after stenosis. Driven by inertial force, reattachment length decreases as the curvature of the parent artery increases, and stream inside the aneurysm is affected only when the distance between stenosis and aneurysm is short enough. In all models, the pressure drop inside the aneurysm increases as the degree of stenosis increases, creating a lower pressure environment in the aneurysm. © 2014 The Japan Society of Mechanical Engineers.

Keyword:

Hemodynamics Computer simulation Blood vessels Flow patterns

Author Community:

  • [ 1 ] [Li, Yujie]College of Life Science and Bioengineering, Beijing University of Technology, 100 Pingleyuan, Chaoyang District, Beijing 100124, China
  • [ 2 ] [Li, Yujie]Graduate School of Engineering, Tohoku University, 6-6 Aramaki Aza Aoba, Aoba-ku, Sendai 980-8579, Japan
  • [ 3 ] [Anzai, Hitomi]Graduate School of Engineering, Tohoku University, 6-6 Aramaki Aza Aoba, Aoba-ku, Sendai 980-8579, Japan
  • [ 4 ] [Nakayama, Toshio]Graduate School of Biomedical Engineering, Tohoku University, 6-6, Aramaki Aza Aoba, Aoba-ku, Sendai 980-8579, Japan
  • [ 5 ] [Shimizu, Yasumoto]Graduate School of Biomedical Engineering, Tohoku University, 6-6, Aramaki Aza Aoba, Aoba-ku, Sendai 980-8579, Japan
  • [ 6 ] [Miura, Yukihisa]Graduate School of Engineering, Tohoku University, 6-6 Aramaki Aza Aoba, Aoba-ku, Sendai 980-8579, Japan
  • [ 7 ] [Qiao, Aike]College of Life Science and Bioengineering, Beijing University of Technology, 100 Pingleyuan, Chaoyang District, Beijing 100124, China
  • [ 8 ] [Ohta, Makoto]Institute of Fluid Science, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Japan

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Source :

Journal of Biomechanical Science and Engineering

ISSN: 1880-9863

Year: 2014

Issue: 1

Volume: 9

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count: 4

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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