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Author:

Liu, Zhaomiao (Liu, Zhaomiao.) (Scholars:刘赵淼) | Zhao, Shengwei (Zhao, Shengwei.) | Li, Yunjie (Li, Yunjie.) | Shen, Feng (Shen, Feng.) | Qi, Yipeng (Qi, Yipeng.) | Wang, Qi (Wang, Qi.)

Indexed by:

EI Scopus SCIE CSCD

Abstract:

Hemodynamics plays a crucial role in the development and progression of coronary atherosclerosis, which is prone to occur in branch bifurcation. An individual aortic-coronary artery model and three changed bifurcation angle models are constructed by Mimics and Freeform based on computed tomography angiography. The influence of different coronary bifurcation angles between left main (LM), left anterior descending (LAD), and left circumflex (LCX) on the blood flow field and related hemodynamic parameters are studied. It is shown that a wider bifurcation angle between LAD and LCX can cause a wider low-wall shear stress area, leading to atherosclerosis. Similarly, a decreased angle between LM and LAD is predisposed to prevent atherosclerosis. The results help to better understand the hemodynamic causes of atherosclerosis with various bifurcation angles in coronary arteries and to provide guidance for clinical assessment and prevention.

Keyword:

Bifurcation angle Coronary artery Atherosclerosis Hemodynamics Wall shear stress

Author Community:

  • [ 1 ] [Liu, Zhaomiao]Beijing Univ Technol, Coll Mech Engn & Appl Elect Technol, Beijing 100124, Peoples R China
  • [ 2 ] [Zhao, Shengwei]Beijing Univ Technol, Coll Mech Engn & Appl Elect Technol, Beijing 100124, Peoples R China
  • [ 3 ] [Li, Yunjie]Beijing Univ Technol, Coll Mech Engn & Appl Elect Technol, Beijing 100124, Peoples R China
  • [ 4 ] [Shen, Feng]Beijing Univ Technol, Coll Mech Engn & Appl Elect Technol, Beijing 100124, Peoples R China
  • [ 5 ] [Qi, Yipeng]Beijing Univ Technol, Coll Mech Engn & Appl Elect Technol, Beijing 100124, Peoples R China
  • [ 6 ] [Wang, Qi]Peoples Liberat Army Gen Hosp, Dept Cardiol, Beijing 100853, Peoples R China

Reprint Author's Address:

  • 刘赵淼

    [Liu, Zhaomiao]Beijing Univ Technol, Coll Mech Engn & Appl Elect Technol, Beijing 100124, Peoples R China

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Source :

ACTA MECHANICA SINICA

ISSN: 0567-7718

Year: 2019

Issue: 6

Volume: 35

Page: 1269-1278

3 . 5 0 0

JCR@2022

ESI Discipline: ENGINEERING;

ESI HC Threshold:136

JCR Journal Grade:3

Cited Count:

WoS CC Cited Count: 12

SCOPUS Cited Count: 14

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 6

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