TA15　alloy,　widely　utilized　in　the　aerospace　industry　for　its　exceptional　mechanical　properties,　was　examined　in　this　study　for　its　anisotropic　microstructure　evolution　and　deformation　behavior　in　laser　melting　deposition　(LMD)-fabricated　samples　at　room　temperature.　Specimens　were　extracted　from　build　(Z-)　and　scanning　(X-)　directions　and　their　microstructures　and　mechanical　properties　were　compared.　A　method　based　on　in-situ　electron　back　scattered　diffraction　(EBSD)　tensile　testing,　was　used　by　inserting　a　tensile　stage　into　scanning　electron　microscopy　(SEM)　to　observe　the　real-time　microstructure　evolution　with　the　change　of　dynamic　tensile　force.　The　evolution　of　slip　bands,　grain　rotation,　grain-to-grain　misorientation,　and　the　dynamic　change　of　mechanical　properties　were　also　systematically　investigated.　The　results　demonstrated　that　the　anisotropic　mechanical　properties　along　the　Z-and　X-directions　in　LMD-fabricated　TA15　alloy　stemmed　from　variations　in　microstructural　anisotropy.　Z-direction　specimen　exhibits　high　elongation　and　reduction　of　cross　section,　whereas,　high　tensile　strength　and　yield　strength　were　identified　in　X-direction.　Furthermore,　the　texture　behavior,　crack　propagation　and　fracture　mechanism　are　discussed　for　each　specimen　orientation.