The　engineering　demands　for　superconductors　require　not　only　a　high　transition　temperature　(Tc)　but　also　eco-friendliness,　mechanical　workability,　and　abundance.　Currently,　superconductors　exhibiting　both　mechanical　ductility　and　Tc　above　the　liquid-nitrogen　temperature　are　still　lacking.　Considering　that　copper　is　one　of　the　most　important　conductive　materials　for　power　transmission,　we　investigate　the　synthetic　routes,　band　topology,　electron-phonon　coupling　(EPC)　and　anharmonic　superconductivity　of　copper　hydrides　using　first-principles　calculations.　Cubic-Cu4H3　remains　stable　at　ambient　pressure　after　kinetic　simulations　from　its　experimentally　synthesized　pressure　state.　The　incorporation　of　hydrogen　impacts　the　ductility　of　Cu4H3　negligibly　compared　to　copper,　while　enabling　high-Tc　superconductivity　up　to　77　K　and　non-trivial　band　topology　at　ambient　pressure.　The　novel　properties　arise　from　the　strong　EPC,　Fermi　surface　nesting　and　hydrogen-induced　band　inversion.　This　discovery　may　fill　the　gap　in　the　lack　of　ductile　superconductors　in　the　liquid-nitrogen　temperature　range　and　pave　a　new　way　for　realizing　high-temperature　topological　superconductivity　at　atmospheric　pressure.