Laser　ablation　accomplishes　high　geometrical　adaptability　by　the　use　of　pulsing　lasers　and　permits　the　manufacture　of　macro-micro-structures.　In　this　paper,　a　systematic　approach　with　a　laser　structuring　technology　was　devised　and　utilized　to　generate　macro-micro-structured　patterns　on　the　diamond　wheel　surface.　An　experiment　on　zirconia　ceramic　grinding　was　performed　by　the　macro-micro-structured　wheel.　The　grinding　force　and　the　surface　morphology　were　investigated.　The　forming　mechanism　of　the　three　grinding　stages　was　analyzed,　including　ductile-stage　grinding,　ductile-to-brittle-transition-stage　grinding　and　brittle-stage　grinding.　A　theoretical　grinding　force　model　was　presented　by　taking　into　account　the　three　grinding　stages　in　laser　macro-micro-structured　grinding　(LMMSG).　In　addition,　the　mean　grinding　depths　were　defined　in　grinding　force　modelling　for　the　ductile　area,　the　ductile-to-brittle-transition　area　and　the　brittle　area,　separately.　The　amount　of　effective　diamond　grains　was　proposed　for　the　final　grinding　force　model.　The　model　revealed　the　connection　between　the　grinding　force　and　the　grinding　parameters.　Finally,　the　model　was　verified　by　experiments,　and　the　experimental　results　were　coincided　with　model　predictions.　It　was　obvious　that　the　theoretical　grinding　force　model　may　be　available　to　predict　the　grinding　force　of　zirconia　ceramics　under　the　LMMSG　condition.　Meanwhile,　the　influence　between　the　grinding　parameters　and　the　surface　morphology　were　discussed.　The　experimental　results　verify　that　the　three　grinding　stages　were　existed　and　the　theoretical　model　was　proved　to　be　reliable.