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Author:

Shen, L. (Shen, L..) | Qiao, A. (Qiao, A..) | Ding, H. (Ding, H..) | Mo, G. (Mo, G..) | Xu, G. (Xu, G..) | Du, Y. (Du, Y..) | Li, M. (Li, M..) (Scholars:栗觅) | Chen, Z. (Chen, Z..) | Zeng, Y. (Zeng, Y..)

Indexed by:

EI Scopus

Abstract:

In order to simulate the hemodynamic environment of human arteries in vivo, we designed a laminar flow apparatus which can precisely simulate the normal stress and shear stress to which cultured endothelial cells are exposed. Under both normal and abnormal physiological conditions, this apparatus can accurately control and adjust the values of normal stress and shear stress and the frequency of pulse waves, as well as the amplitude of pulsatile flow. This in vitro apparatus provides an experimental platform for studying the response of the biological characteristics of cultured endothelial cells in a hemodynamic environment. Copyright © 2006 ACPSEM/EA.

Keyword:

Body fluids Physiology Shear stress Hemodynamics Pulsatile flow Computer simulation Cell culture

Author Community:

  • [ 1 ] [Shen, L.]Biomechanics and Medical Information Institute, Beijing University of Technology, Beijing 100022, China
  • [ 2 ] [Shen, L.]The Medical Instrumentation College, University of Shanghai for Science and Technology, Shanghai, China
  • [ 3 ] [Qiao, A.]Biomechanics and Medical Information Institute, Beijing University of Technology, Beijing 100022, China
  • [ 4 ] [Ding, H.]The Medical Instrumentation College, University of Shanghai for Science and Technology, Shanghai, China
  • [ 5 ] [Mo, G.]The Medical Instrumentation College, University of Shanghai for Science and Technology, Shanghai, China
  • [ 6 ] [Xu, G.]The Medical Instrumentation College, University of Shanghai for Science and Technology, Shanghai, China
  • [ 7 ] [Du, Y.]The Medical Instrumentation College, University of Shanghai for Science and Technology, Shanghai, China
  • [ 8 ] [Li, M.]The Medical Instrumentation College, University of Shanghai for Science and Technology, Shanghai, China
  • [ 9 ] [Chen, Z.]The Medical Instrumentation College, University of Shanghai for Science and Technology, Shanghai, China
  • [ 10 ] [Zeng, Y.]Biomechanics and Medical Information Institute, Beijing University of Technology, Beijing 100022, China

Reprint Author's Address:

  • [zeng, y.]biomechanics and medical information institute, beijing university of technology, beijing 100022, china

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Source :

Australasian Physical and Engineering Sciences in Medicine

ISSN: 0158-9938

Year: 2006

Issue: 2

Volume: 29

Page: 196-202

ESI Discipline: MOLECULAR BIOLOGY & GENETICS;

Cited Count:

WoS CC Cited Count: 0

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 5

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