The　interaction　between　solutes　and　membrane,　the　major　reason　of　flux　decline　during　dead-end　microfiltration,　and　the　separation　mechanisms　were　introduced　firstly.　We　discussed　systematically　the　models　such　as　blocking　model,　series　resistance　model　and　others.　The　models　such　as　blocking　model,　resistance-in-series　model　and　others　were　discussed　systematically.　The　advantages　and　disadvantages　of　all　kinds　of　models　were　compared　and　brief　comments　on　their　development　were　made.