A　large　number　of　simulation　experiments　were　required　for　specialized　practices.　Currently,　those　experiments　are　operated　in　laboratories　with　real　existed　experimental　equipment.　However,　this　method　render　disadvantages　in　safety　concern,　economic　concern　and　convenience　concern.　We　proposes　a　method　for　realizing　a　industrial　simulation　system　based　on　the　Building　Information　Modeling　(BIM)　technology　and　the　Functional　Mock-Up　Unit　(FMU),　which　can　be　applied　to　many　industrial　fields.　To　verify　this　method,　we　have　a　thorough　study　on　the　visualization　approach　for　airflow　ventilation　system,　and　then　studied　various　user　interacts　in　airflow　ventilation　system　using　Three-Dimensional　Interaction　Technology.　In　the　last,　we　propose　a　method　for　information　exchange　between　FMU　and　simulation　system　to　realize　the　real　time　simulation　of　airflow　ventilation　system.　©　2019　IEEE.