This　paper　presents　a　novel　application　of　a　perception　sensor　Leap　Motion　to　a　mobile　tool　cart　(MTC).　Daily-used　instructions　are　exercised　as　commands　to　control　the　MTC　in　the　factory　environment　by　using　finger/hand　position　detection　of　the　Leap　Motion.　A　type　of　differential-driven　mobile　cart　with　a　tool　basket　which　is　mounted　on　the　top　of　the　mobile　cart　comprise　the　mobile　tool　cart.　The　commercialized　Leap　Motion　sensor　is　employed　to　detect　hand/finger　gestures　of　the　worker.　In　the　same　WiFi　environment,　the　worker　uses　Leap　Motion　sensor　which　is　equipped　on　the　operation　platform　to　give　different　remote　commands,　for　example,　Go　Forward,　Draw　Back,　Turn　Left,　Turn　Right,　Start/Stop,　Acceleration　and　Deceleration　to　the　MTC.　We　define　a　set　of　trajectory　determined　by　the　hand/finger　commend　of　the　worker　to　do　the　reflexes　and　the　experiment　result　shows　the　validity　of　proposed　method.　©　2018　IEEE.