Skin　resistance　is　one　of　the　important　indexes　in　psychological　affective　researches,　and　it　can　reflect　the　change　of　emotion　by　recording　its　changes.　Generally,　the　skin　resistance　measurement　method　is　connecting　the　electrode　sensor　to　the　two　adjacent　fingers　of　the　object　to　record　the　resistance　signal,　and　then　amplifying,　collecting　and　recording　the　signal　by　amplification　circuit.　However,　the　study　found　that　in　the　actual　measurement　process,　the　skin　resistance　can　produce　non-emotional　impact　changes　caused　by　the　signal　acquisition　error　and　temperature　fluctuation　factors;　thereby　the　actual　measurement　results　can　be　interfered.　This　study　improved　the　selection　of　sensor　module　and　the　amplification　circuits　to　deal　with　this　problem.　As　for　the　acquisition　of　signal,　this　study　adopts　the　pet　polyethylene　glycol　ester　containing　activated　carbon　as　the　electrode　sensor　material　and　selects　the　palm　area　as　the　signal　collecting　site;　as　for　the　amplification　circuit,　the　differential　amplification　circuit　which　can　restrain　the　drift　effectively　was　chosen　to　realize　the　amplification　signal　function.　The　comparison　experiment　shows　that　the　improved　acquisition　sensor　module　and　differential　amplification　circuit　can　effectively　improve　the　anti-interference　ability　of　the　skin　resistance　measuring　device.　Finally,　this　study　proves　that　the　experimental　device　can　effectively　measure　the　emotional　changes　of　the　object　by　using　the　experiment　of　fear　and　happy　emotional　stimuli.　©　2017　IEEE.