To　investigate　the　effects　of　arterial　wall　thickness　on　pulse　wave　propagation.　The　unsteady　flow　was　assumed　to　be　laminar,　Newtonian,　viscous　and　incompressible.　The　vessel　wall　was　assumed　to　be　linear-elastic,　isotropic　and　incompressible.　The　fluid-wall　interaction　algorithm　was　constructed　and　the　finite　element　method　was　employed.　The　results　show　that　the　increase　of　wall　thickness　makes　pulse　wave　propagation　fasten　and　the　time　delay　could　not　be　observed.　The　results　indicate　that　the　effects　of　arterial　wall　thickness　on　pulse　wave　propagation　are　significant.　The　fluidwall　interaction　model　simulates　wave　propagation　successfully.