Objective　To　study　effects　of　different　inlet　and　outlet　conditions　on　fluid-wall　interaction　models　in　hemodynamics.　Method　The　finite　element　method　was　employed.　According　to　different　inlet　and　outlet　conditions,　several　groups　were　divided　and　numerical　experiments　were　done.　Results　The　distributions　of　blood　flow　velocity　are　blunt;　The　blood　pressure　changes　are　different,　and　reflection　is　presented　in　a　certain　pressure　waveform;　The　stresses　and　strains　of　blood　vessel　wall　are　caused　by　the　blood　pressure　and　they　reflect　the　change　trend　and　waveform　of　the　pressure.　Conclusion　The　effects　of　inlet　and　outlet　conditions　on　fluid-wall　interaction　models　in　hemodynamics　are　significant　and　the　conditions　can　affect　flow　field　distributions.　©　2008　IEEE.