By　utilizing　the　high　gas　permeability　of　polydimethylsiloxane　(PDMS),　a　simple　positive　pressure-driven　pumping　method　was　introduced.　The　pump　was　an　aerated　PDMS　with　a　central　channel　in　it　and　packing　with　a　transfusion　bottle.　It　could　be　attached　to　the　inlet　of　microfluidic　chip　using　a　Teflon　tube　to　release　the　air　into　the　microfluidic　system　and　then　to　create　a　positive　pressure　for　driving　fluid.　In　comparison　with　the　degas-based　PDMS　pump,　positive　pressure-driven　PDMS　pump　offered　increased　system　flexibility　and　reduced　individual　device　fabrication　complexity　due　to　its　independence　and　versatility.　More　importantly,　it　offered　the　advantages　that　the　PDMS　pump　could　be　wrapped　in　transfusion　bottles　to　meet　the　readily　available　requirements,　and　it　also　easily　assembled,　which　only　required　the　user　use　a　Teflon　tube　to　connect　a　PDMS　pump　and　a　microfluidic　chip.　This　assembly　provided　great　freedom　to　meet　different　pumping　requirements.　Furthermore,　this　PDMS　pump　could　offer　many　possible　configures　of　pumping　power　by　adjusting　the　geometries　of　the　pump　or　by　combining　different　pump　modules,　the　adjustment　of　pumping　capacity　was　investigated.　To　help　design　pumps　with　a　suitable　pumping　performance,　the　sealing　effect,　pumping　pressure　and　flow　rate　were　also　investigated.　The　results　indicated　that　the　performance　of　the　positive　pressure-driven　PDMS　pump　was　reliable.　Finally,　we　demonstrated　the　utility　of　this　pumping　method　by　applying　it　to　a　PDMS-based　viscometer　microfluidic　chip.