• Complex
  • Title
  • Keyword
  • Abstract
  • Scholars
  • Journal
  • ISSN
  • Conference
搜索

Author:

Zhang, Qi (Zhang, Qi.) | Gao, Bin (Gao, Bin.) | Chang, Yu (Chang, Yu.) (Scholars:常宇)

Indexed by:

Scopus SCIE

Abstract:

Background: Although LVADs are confirmed to have strong effects on aortic hemodynamics, the precise mechanisms of the helical flow component of LVAD outflow are still unclear. Material/Methods: To clarify these effects, 3 cases - normal case, flat flow case, and realistic flow case - were designed and studied by using the CFD approach. The normal case denoted the normal aorta without LVAD support, and the flat flow case represented the aorta with the outflow cannula. Similarly, the realistic flow case included the aortic model, the model of outflow cannula, and the model of LVAD. The velocity vector, blood streamline, distribution of wall shear stress (WSS), and the local normalized helicity (LNH) were calculated. Results: The results showed that the helical component of LVAD outflow significantly improved the aortic hemodynamics. Compared with the flat flow case, the helical flow eliminated the vortex near the outer wall of the aorta and improved the blood flow transport (normal case 0.1 m/s vs. flat flow case 0.14 m/s vs. realistic flow case 0.30 m/s) at the descending aorta. Moreover, the helical flow was confirmed to even the distribution of WSS, reduce the peak value of WSS (normal case 0.92 Pa vs. flat flow case 7.39 Pa vs. realistic flow case 5.2Pa), and maintain a more orderly WSS direction. Conclusions: The helical flow component of LVAD outflow has significant advantages for improving aortic hemodynamic stability. Our study provides novel insights into LVAD optimization.

Keyword:

Finite Element Analysis Hemodynamics Heart, Artificial

Author Community:

  • [ 1 ] [Zhang, Qi]Beijing Univ Technol, Sch Life Sci & Bioengn, Beijing, Peoples R China
  • [ 2 ] [Gao, Bin]Beijing Univ Technol, Sch Life Sci & Bioengn, Beijing, Peoples R China
  • [ 3 ] [Chang, Yu]Beijing Univ Technol, Sch Life Sci & Bioengn, Beijing, Peoples R China

Reprint Author's Address:

  • [Gao, Bin]Beijing Univ Technol, Sch Life Sci & Bioengn, Beijing, Peoples R China

Show more details

Related Keywords:

Related Article:

Source :

MEDICAL SCIENCE MONITOR

ISSN: 1643-3750

Year: 2018

Volume: 24

Page: 869-879

3 . 1 0 0

JCR@2022

ESI Discipline: CLINICAL MEDICINE;

ESI HC Threshold:167

JCR Journal Grade:3

Cited Count:

WoS CC Cited Count: 10

SCOPUS Cited Count: 11

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 7

Online/Total:856/10803038
Address:BJUT Library(100 Pingleyuan,Chaoyang District,Beijing 100124, China Post Code:100124) Contact Us:010-67392185
Copyright:BJUT Library Technical Support:Beijing Aegean Software Co., Ltd.